Welcome to the Sanjeev's Lab at the Alagappa University’s Department of Bioinformatics. Our group are interested to improve the treatment and developing novel therapeutics from basic research to molecular level for the study of interactive small chemicals inhibitors with infectious diseases. Our team design inhibitors to impede the functional importance of drug targets using in-silico approaches including Molecular Modelling, Docking Simulation, ADME/T generation, MO/DFT/QM/MM prediction, Free energy calculation, Pharmacophore mapping & QSAR studies. In order to develop new models, Ab initio Quantum calculation, 3D-database searching & development, combinatorial library design, Optimization of lead compounds generated massive libraries of small molecules to screen against specific therapeutic processes.
Our energetic environment of team work is focused to gain the experience and knowledge for developing research strategies for predicting interactions between drugs and proteins, analysis of impact on biological pathways and functions. Along with the national and international collaborators, our research is also active in development of various antiviral, antibacterial and anticancer drug like agents.